circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA.2837
Host Gene: rno-miR-34
 
 
 
Disease basic information
DO ID:
 11446
DO name: sciatic neuropathy
Disease details: sciatic nerve injury
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: rno-miR-34
Biological function: knockdown of circRNA.2837 may protect neurons against neurological injury
Molecular mechanism: acting as a sponge for members of miR-34 family
Survival: -
Supported No.:
 1
Description:

Our findings suggested that differentially expressed circular RNAs were involved in the pathogenesis of sciatic nerve injury, and circular RNAs exerted regulatory functions in sciatic nerve injury and might be used as potential targets in sciatic nerve injury therapy.
Other information
Title:

Silencing of circRNA2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy.

Journal: Mol Ther Nucleic Acids
Published: 2018/8/12
PubMed ID: 30098504