circRNA basic information
circBase ID: hsa_circ_0000144
Name: hsa_circ_SLAMF6
Synonym: -
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Bladder cancer cell lines (T24, EJ, UMUC3, RT4, 253J), SV-HUC-1 cells
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: RUNX2
Associated microRNA: hsa-miR-217
Biological function: promoted the proliferation, invasion
Molecular mechanism: repressing hsa-miR-217 to facilitate RUNX2 expression
Survival: poor
Supported No.:
 1
Description:

these findings demonstrated that hsa_circ_0000144 exerts oncogenic roles in bladder cancer via repressing miR-217 to facilitate RUNX2 expression.
Other information
Title:

Downregulation of circular RNA hsa_circ_0000144 inhibits bladder cancer progression via stimulating miR-217 and suppressing RUNX2 expression.

Journal: Gene
Published: 2018/8/12
PubMed ID: 30098434