circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_15698
Host Gene: hsa-miR-185
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: diabetic nephropathy
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: mouse MCs (SV40_MES13)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: TGF-beta1
Associated microRNA: hsa-miR-185
Biological function: -
Molecular mechanism: circRNA_15698/hsa-miR-185/TGF-beta1 pathway
Survival: -
Supported No.:
 1
Description:

In summary, our study preliminarily investigates the role of circRNAs in mesangial cells and ECM accumulation, providing a novel insight for DN pathogenesis.
Other information
Title:

Circular RNA circRNA_15698 aggravates the extracellular matrix of diabetic nephropathy mesangial cells via miR-185/TGF-beta1.

Journal: J Cell Physiol
Published: 2018/7/29
PubMed ID: 30054916