circRNA basic information
circBase ID: -
Name: hsa_circ_DLEU2
Synonym: circRNA-DLEU2
Host Gene: hsa-miR-496
 
 
 
Disease basic information
DO ID:
 9119
DO name: acute myeloid leukemia
Disease details: acute myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human AML cell lines (MOLM-13, MV-4-11, HL-60), normal cells (BMSC), HEK293
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PRKACB
Associated microRNA: hsa-miR-496
Biological function: promoted AML cell proliferation and inhibited cell apoptosis
Molecular mechanism: suppressing hsa-miR-496 and promoting PRKACB expression
Survival: -
Supported No.:
 2
Description:

CircRNA-DLEU2 accelerated human AML by suppressing miR-496 and promoting PRKACB expression.
Other information
Title:

Role of Circular RNA DLEU2 in Human Acute Myeloid Leukemia.

Journal: Mol Cell Biol
Published: 2018/7/25
PubMed ID: 30037980