circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_11897
Host Gene: ssc-miR-27a, ssc-miR-27b-3p
 
 
 
Disease basic information
DO ID:
 0014667
DO name: disease of metabolism
Disease details: metabolism-related diseases
Species: others
Species details: pig
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: ssc-miR-27a, ssc-miR-27b-3p
Biological function: -
Molecular mechanism: lipid metabolism, MAPK cascade reaction, ERK1 and ERK2 cascade reaction, cell proliferation, PPAR signaling pathway, AMPK signaling pathway, non-alcoholic fatty liver disease (NAFLD), Alzheimer disease, pathways in cancer
Survival: -
Supported No.:
 1
Description:

In this study, circRNA sequencing and bioinformatics technique were used to analyze, for the first time, the expression of circRNAs in the subcutaneous adipose tissues of Large White pig and Laiwu pig. It is inferred that circRNAs might regulate adipogenic differentiation and lipid metabolism. The results provide a theoretical basis for further study on fat deposition mechanism and provide potential therapy targets for metabolism-related diseases.
Other information
Title:

Identification and Characterization of CircRNAs of Two Pig Breeds as a New Biomarker in Metabolism-Related Diseases.

Journal: Cell Physiol Biochem
Published: 2018/7/11
PubMed ID: 29990990