circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_26852
Host Gene: ssc-miR-874, ssc-miR-486
 
 
 
Disease basic information
DO ID:
0014667
DO name: disease of metabolism
Disease details: metabolism-related diseases
Species: others
Species details: pig
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: ssc-miR-874, ssc-miR-486
Biological function: -
Molecular mechanism: fat deposition and lipid metabolism, biosynthesis of unsaturated fatty acids, fatty acid metabolism, PPAR signaling pathway, TGF-beta signaling pathway, and disease-related signaling pathways
Survival: -
Supported No.:
1
Description:

In this study, circRNA sequencing and bioinformatics technique were used to analyze, for the first time, the expression of circRNAs in the subcutaneous adipose tissues of Large White pig and Laiwu pig. It is inferred that circRNAs might regulate adipogenic differentiation and lipid metabolism. The results provide a theoretical basis for further study on fat deposition mechanism and provide potential therapy targets for metabolism-related diseases.

Other information
Title:

Identification and Characterization of CircRNAs of Two Pig Breeds as a New Biomarker in Metabolism-Related Diseases.

Journal: Cell Physiol Biochem
Published: 2018/7/11
PubMed ID: 29990990