circRNA basic information
circBase ID: -
Name: -
Synonym: circ_001569
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NSCLC cell lines (H460, H1299, SPC-A1, A549), non-tumorigenic bronchial epithelium cell line (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell proliferation
Molecular mechanism: regulating the Wnt/beta-catenin pathway
Survival: poor
Supported No.:
 1
Description:

Therefore, the results indicated that circ_001569 promoted cell proliferation by regulating the Wnt/beta-catenin pathway in NSCLC, and circ_001569 may be a potential target of NSCLC treatment.
Other information
Title:

Upregulation of circ_001569 predicts poor prognosis and promotes cell proliferation in non-small cell lung cancer by regulating the Wnt/beta-catenin pathway.

Journal: Oncol Lett
Published: 2018/6/22
PubMed ID: 29928432