circRNA basic information
circBase ID: hsa_circ_0016788
Name: hsa_circ_TRIM11
Synonym: -
Host Gene: hsa-miR-486
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human HCC cell lines (HepG2, Hep3B, Huh7, HCCLM3, MHCC97L), normal liver cell lines (LO2)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: CDK4
Associated microRNA: hsa-miR-486
Biological function: promoted the proliferation, invasion and inhibited the apoptosis
Molecular mechanism: hsa_circ_0016788/hsa-miR-486/CDK4 pathway
Survival: -
Supported No.:
 2
Description:

In summary, results reveal the role of hsa_circ_0016788/miR-486/CDK4 in HCC tumorigenesis, providing a novel therapeutic target for HCC.
Other information
Title:

Circular RNA hsa_circ_0016788 regulates hepatocellular carcinoma tumorigenesis through miR-486/CDK4 pathway.

Journal: J Cell Physiol
Published: 2018/6/21
PubMed ID: 29923236