circRNA basic information
circBase ID: hsa_circ_0001649
Name: hsa_circ_SHPRH
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human RB cell lines (SO-Rb50, HXO-RB44), human retinal pigment epithelial cell line (ARPE-19)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: AKT
Associated microRNA: -
Biological function: inhibits cell growth and promotes cell apoptosis in RB cells
Molecular mechanism: modulating AKT/mTOR signaling pathway
Survival: better
Supported No.:
 1
Description:

Downregulation of circular RNA hsa_circ_0001649 indicates poor prognosis for retinoblastoma and regulates cell proliferation and apoptosis via AKT/mTOR signaling pathway.
Other information
Title:

Downregulation of circular RNA hsa_circ_0001649 indicates poor prognosis for retinoblastoma and regulates cell proliferation and apoptosis via AKT/mTOR signaling pathway.

Journal: Biomed Pharmacother
Published: 2018/6/5
PubMed ID: 29864621