circRNA basic information
circBase ID: -
Name: hsa_circ_SMAD2
Synonym: -
Host Gene: hsa-miR-629
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCC cell lines (HepG2, HCCLM9, HCCLM3, MHCC97L), immortalized human hepatic cell line (L02)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-629
Biological function: inhibits the migration, invasion, and EMT
Molecular mechanism: inhibits the epithelial-mesenchymal transition by targeting hsa-miR-629
Survival: -
Supported No.:
 1
Description:

Altogether, our data support that circSMAD2 inhibits the migration, invasion, and EMT of HCC cells by targeting miR-629.
Other information
Title:

circSMAD2 inhibits the epithelial-mesenchymal transition by targeting miR-629 in hepatocellular carcinoma.

Journal: Onco Targets Ther
Published: 2018/5/31
PubMed ID: 29844683