circRNA basic information
circBase ID: hsa_circ_0071589
Name: hsa_circ_FAT1
Synonym: -
Host Gene: hsa-miR-600
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human colon cancer cell line (HCT116)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EZH2
Associated microRNA: hsa-miR-600
Biological function: promote cell growth, invasion and migration
Molecular mechanism: modulating hsa-miR-600/EZH2 axis
Survival: -
Supported No.:
 2
Description:

These results demonstrated that the hsa_circ_0071589/miR-600/EZH2 axis may play critical regulatory roles in the pathogenesis of CRC and may serve as a novel therapy target in CRC.
Other information
Title:

Hsa_circ_0071589 promotes carcinogenesis via the miR-600/EZH2 axis in colorectal cancer.

Journal: Biomed Pharmacother
Published: 2018/5/2
PubMed ID: 29710537