circRNA basic information
circBase ID: -
Name: -
Synonym: mm9_circ_009056
Host Gene: hsa-miR-22-3p
 
 
 
Disease basic information
DO ID:
12347
DO name: osteogenesis imperfecta
Disease details: enhances osteogenesis
Species: human
Species details: human
Sample type: cell line
Sample type details: MC3T3-E1 cells
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: BMP7, RUNX2
Associated microRNA: hsa-miR-22-3p
Biological function: enhances osteogenesis
Molecular mechanism: decreased the expression of hsa-miR-22-3p and increased the gene and protein levels of BMP7, RUNX2.
Survival: -
Supported No.:
1
Description:

mm9_circ_009056 may function as a sponge for miR-22-3p to regulate osteogenesis in CGRP-induced cells.

Other information
Title:

Mm9_circ_009056 enhances osteogenesis by targeting BMP7 via CGRP-mediated miR-22-3p.

Journal: Biochem Biophys Res Commun
Published: 2018/5/2
PubMed ID: 29709471