circRNA basic information
circBase ID: -
Name: hsa_circ_FADS2
Synonym: hsa_circRNA_100833
Host Gene: hsa-miR-498
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NSCLC cell lines (A549, SK-MES-1, H1299, NCI-H1975), normal human osteoplastic cell line (NHOst)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-498
Biological function: promote lung cancer cells proliferation and invasion
Molecular mechanism: acting as a sponge of hsa-miR-498
Survival: poor
Supported No.:
 1
Description:

Taken together, our findings indicated that circFADS2 was an effective tumor promoter in lung cancer progression, and its functions were performed by regulating the expression of miR-498. These data suggested that circFADS2 could act as a target for lung cancer treatment.
Other information
Title:

circFADS2 regulates lung cancer cells proliferation and invasion via acting as a sponge of miR-498.

Journal: Biosci Rep
Published: 2018/4/28
PubMed ID: 29700215