circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_103809
Host Gene: hsa-miR-4302
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: lung cancer cell lines (A549, H125, 95D, NCI-H292, H1975), normal human bronchus epithelium cell line (HBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZNF121, MYC
Associated microRNA: hsa-miR-4302
Biological function: contributed to lung cancer cell proliferation and invasion
Molecular mechanism: facilitating ZNF121-dependent MYC expression by sponging hsa-miR-4302
Survival: poor
Supported No.:
 1
Description:

In conclusion, our findings illustrated a novel hsa_circRNA_103809/miR-4302/ZNF121/MYC regulatory signaling pathway in lung cancer progression.
Other information
Title:

Circular RNA hsa_circRNA_103809 promotes lung cancer progression via facilitating ZNF121-dependent MYC expression by sequestering miR-4302.

Journal: Biochem Biophys Res Commun
Published: 2018/4/27
PubMed ID: 29698681