circRNA basic information
circBase ID: -
Name: hsa_circ_NASP
Synonym: -
Host Gene: hsa-miR-1253
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human osteosarcoma cell lines (143B, MG63)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXF1
Associated microRNA: hsa-miR-1253
Biological function: promote to the proliferation, cell cycle progression and invasion of OS cells
Molecular mechanism: circNASP acts as a sponge of hsa-miR-1253 targeting FOXF1 in OS cells
Survival: -
Supported No.:
 1
Description:

Taken together, our findings demonstrated that circNASP contributes to malignant behaviors of OS cells by miR-1253/FOXF1 pathway, which suggested circNASP/miR-1253/FOXF1axis might be a potential therapeutic target.
Other information
Title:

Circular RNA circNASP modulates the malignant behaviors in osteosarcoma via miR-1253/FOXF1 pathway.

Journal: Biochem Biophys Res Commun
Published: 2018/4/22
PubMed ID: 29678578