circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_100284
Host Gene: hsa-miR-217
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: malignant transformation of human hepatic cells
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: L-02 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-217
Biological function: accelerating the cell cycle and promoting cell proliferation
Molecular mechanism: via microRNA-217 regulation of EZH2
Survival: -
Supported No.:
 1
Description:

The findings support the concept that exosomal circRNAs are involved in cell-cell communication during carcinogenesis induced by arsenite.
Other information
Title:

Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation.

Journal: Cell Death Dis
Published: 2018/4/21
PubMed ID: 29674685