circRNA basic information
circBase ID: -
Name: hsa_circ_CDK13
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3571
DO name: liver cancer
Disease details: liver cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MHCC97-H, MHCC97-L, SMCC7721, normal liver cell line (L-02)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: JAK, STAT, PI3K
Associated microRNA: -
Biological function: suppresses cell proliferation, migration and invasion
Molecular mechanism: modulating the JAK/STAT and PI3K/AKT pathways
Survival: -
Supported No.:
 1
Description:

On the whole, the findings of this study indicate that circCDK13 is a novel circular RNA that suppresses liver cancer progression, and that these suppressive effects are possibly mediated via the JAK/STAT and PI3K/AKT signaling pathways.
Other information
Title:

Circular RNA circCDK13 suppresses cell proliferation, migration and invasion by modulating the JAK/STAT and PI3K/AKT pathways in liver cancer.

Journal: Int J Oncol
Published: 2018/4/17
PubMed ID: 29658568