circRNA basic information
circBase ID: -
Name: -
Synonym: circ-4099
Host Gene: hsa-miR-616-5p
 
 
 
Disease basic information
DO ID:
 90
DO name: degenerative disc disease
Disease details: intervertebral disc degeneration
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: Collagen II, Aggrecan, IL-1beta, TNF-alpha, PGE2, MAPK, GRP78
Associated microRNA: hsa-miR-616-5p
Biological function: regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circular RNA circ-4099 is induced by TNF-alpha and regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9 in intervertebral disc degeneration.
Other information
Title:

Circular RNA circ-4099 is induced by TNF-alpha and regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9 in intervertebral disc degeneration.

Journal: Exp Mol Med
Published: 2018/4/14
PubMed ID: 29651107