circRNA basic information
circBase ID: hsa_circ_0014717
Name: hsa_circ_CCT3
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (HCT116, HT29, SW480)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: p16
Associated microRNA: -
Biological function: suppressed cell proliferation
Molecular mechanism: promoting p16 expression
Survival: better
Supported No.:
 2
Description:

Taken together, hsa_circ_0014717 acts as a potential tumor suppressor that inhibits CRC growth, partly at least, through upregulating p16 expression. Furthermore, our present study may provide a promising therapeutic target for CRC patients.
Other information
Title:

Hsa_circ_0014717 is downregulated in colorectal cancer and inhibits tumor growth by promoting p16 expression.

Journal: Biomed Pharmacother
Published: 2018/3/25
PubMed ID: 29571246