circRNA basic information
circBase ID: -
Name: hsa_circ_ATP2B1
Synonym: -
Host Gene: hsa-miR-204-3p
 
 
 
Disease basic information
DO ID:
 4467
DO name: clear cell renal cell carcinoma
Disease details: clear cell renal cell carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: 786-O, A498, Caki-1, HEK-293
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: Erbeta
Associated microRNA: hsa-miR-204-3p
Biological function: promotes cell invasion
Molecular mechanism: ERbeta increased ccRCC cell invasion via suppression of circular RNA ATP2B1 (circATP2B1) expression by binding directly to the 5 promoter region of its host gene ATPase plasma membrane Ca2(+) transporting 1 (ATP2B1)
Survival: -
Supported No.:
 1
Description:

These results identify an ERbeta/circATP2B1/miR-204-3p/FN1 signaling axis in RCC, suggesting ERbeta and circular RNA ATP2B1 as prognostic biomarkers for this disease.
Other information
Title:

ERbeta-Mediated Alteration of circATP2B1 and miR-204-3p Signaling Promotes Invasion of Clear Cell Renal Cell Carcinoma.

Journal: Cancer Res
Published: 2018/3/2
PubMed ID: 29490945