circRNA basic information
circBase ID: hsa_circ_0050263
Name: -
Synonym: circ_0050263
Host Gene: hsa-miR-361-3p
 
 
 
Disease basic information
DO ID:
 10652
DO name: Alzheimer disease
Disease details: Alzheimer disease
Species: human
Species details: human
Sample type: cell line
Sample type details: Human neuroblastoma cell line SK-N-SH
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PDE4A
Associated microRNA: hsa-miR-361-3p
Biological function: we found that Res treatment alleviated Abeta-induced apoptosis, inflammatory response, oxidative stress, and ERS in SK-N-SH cells
Molecular mechanism: circ_0050263 acted as a sponge for miR-361-3p, which targeted PDE4A.
Survival: -
Supported No.:
 1
Description:

Res alleviated Abeta-induced neuronal apoptosis, inflammation, oxidative stress, and ERS via circ_0050263/miR-361-3p/PDE4A axis, providing new insights for AD therapy.
Other information
Title:

Resveratrol alleviates amyloid beta-induced neuronal apoptosis, inflammation, and oxidative and endoplasmic reticulum stress by circ_0050263/miR-361-3p/PDE4A axis during Alzheimer disease.

Journal: Chem Biol Drug Des
Published: 2023/8/25
PubMed ID: 37620166