circRNA basic information
circBase ID: hsa_circ_0001535
Name: hsa_circ_FAM13B
Synonym: circ_0001535
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10652
DO name: Alzheimer disease
Disease details: Alzheimer disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human neuroblastoma cells (SH-SY5Y)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F1, DHFR
Associated microRNA: -
Biological function: circ_0001535 could reduce Abeta25-35-induced SH-SY5Y cell proliferation and facilitate apoptosis through E2F1/DHFR axis
Molecular mechanism: circ_0001535/E2F1/DHFR axis
Survival: -
Supported No.:
 1
Description:

Our research in AD circRNA can offer important information regarding the role of specific circRNAs in the AD environment and point to specific future areas of therapeutic intervention in AD
Other information
Title:

Bioinformatics and Experimental Identification of circ_0001535 Associated with Diagnosis and Development of Alzheimer Disease

Journal: J Integr Neurosci
Published: 2023/7/26
PubMed ID: 37519165