circRNA basic information
circBase ID: hsa_circ_0000073
Name: hsa_circ_OMA1
Synonym: -
Host Gene: hsa-miR-1184
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MG-63, Saos-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FADS2
Associated microRNA: hsa-miR-1184
Biological function: Moreover, the higher expression of hsa_circ_0000073 was associated with worse survival rates, advanced clinical stage, large tumor size, and metastasis.
Molecular mechanism: lipid metabolism
Survival: -
Supported No.:
 4
Description:

Our study revealed that hsa_circ_0000073 contributed to the lipid synthesis of osteosarcoma by decreasing the expression of miR-1184, thereby increasing FADS2, which provides new insights into treating osteosarcoma.
Other information
Title:

Hsa_circ_0000073 promotes lipid synthesis of osteosarcoma through hsa-miR-1184/ FADS2 pathway

Journal: Cell Signal
Published: 2023/7/26
PubMed ID: 37506860