circRNA basic information
circBase ID: hsa_circ_0004951
Name: hsa_circ_TRPM7
Synonym: circTRPM7
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric cancer cell lines (HGC-27, AGS), gastric mucosa cells (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PBX3
Associated microRNA: hsa-miR-145-5p
Biological function: Moreover, overexpression of circTRPM7 upregulated the growth and metastasis of Sinomenine-treated gastric cancer cells.
Molecular mechanism: circTRPM7/hsa-miR-145-5p/PBX3 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

To sum up, our data indicated that Sinomenine played an antitumor role in gastric cancer cells via circTRPM7/miR-145-5p/PBX3 axis.
Other information
Title:

Sinomenine regulates circTRPM7-related pathway to inhibit gastric cancer cell growth and metastasis

Journal: Chem Biol Drug Des
Published: 2023/7/26
PubMed ID: 37495546