circRNA basic information
circBase ID: hsa_circ_0001722
Name: hsa_circ_CDK14
Synonym: -
Host Gene: hsa-miR-204-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human OS cell lines (MG63, U2OS), a normal human fetal osteoblastic cell line (hFOB1.19), human embryonic kidney cell line (HEK293T)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: RUNX2
Associated microRNA: hsa-miR-204-5p
Biological function: Downregulation of circ_0001722 can suppress proliferation and invasion of human OS cells in vitro and in vivo
Molecular mechanism: Circ_001722/hsa-miR-204-5p/RUNX2 axis, miRNA sponge
Survival: -
Supported No.:
 5
Description:

Circ_001722 is a novel tumor promotor in OS, and promotes the progression of OS via miR-204-5p/RUNX2 axis.
Other information
Title:

A novel CircRNA Circ_0001722 regulates proliferation and invasion of osteosarcoma cells through targeting miR-204-5p/RUNX2 axis

Journal: J Cancer Res Clin Oncol
Published: 2023/7/15
PubMed ID: 37453970