circRNA basic information
circBase ID: -
Name: mmu_circ_Cmss1
Synonym: circCmss1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: cardiac hypertrophy
Species: mouse
Species details: mouse
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: EIF4A3, TfR1
Associated microRNA: -
Biological function: Angiotensin II(Ang II)induced neonatal cardiomyocyte hypertrophy in vitro and the pressure overload-induced cardiac hypertrophy in vivo can be reduced by Knocking down circCmss1
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

This study highlights the significance of NSD2 activation of circCmss1/EIF4A3/TfR1 as therapeutic targets for treating pathological myocardial hypertrophy.
Other information
Title:

NSD2 promotes pressure overload-induced cardiac hypertrophy via activating circCmiss1/TfR1/ferroptosis signaling.

Journal: Life Sci
Published: 2023/6/24
PubMed ID: 37352916