circRNA basic information
circBase ID: hsa_circ_0001741
Name: hsa_circ_TNPO3
Synonym: circ_0001741
Host Gene: hsa-miR-188-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal ovarian epithelial cells (IOSE8, OC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXN2
Associated microRNA: hsa-miR-188-5p
Biological function: hsa_circ_0001741 upregulation resulted in OC proliferation inhibitions
Molecular mechanism: hsa_circ_0001741/hsa-miR-188-5p/FOXN2 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Therefore our data suggested that hsa_circ_0001741 upregulation inhibited proliferation of OC through modulatory effects on miR-188-5p/FOXN2 signaling.
Other information
Title:

Hsa_circ_0001741 Suppresses Ovarian Cancer Cell Proliferations Through Adsorption of miR-188-5p and Promotion of FOXN2 Expression.

Journal: Mol Biotechnol
Published: 2023/6/15
PubMed ID: 37318741