circRNA basic information
circBase ID: hsa_circ_0038467
Name: -
Synonym: circ_0038467
Host Gene: hsa-miR-203
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: cell line
Sample type details: chondrocytes
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-203
Biological function: Circ_0038467 directly interacted with the precursor miR-203.
Molecular mechanism: overexpression of Circ_0038467 increased the expression levels of mature miR-203 but not that of miR-203 precursor. Overexpression of Circ_0038467 and miR-203 increased cell apoptosis.
Survival: -
Supported No.:
 1
Description:

Circ_0038467 is highly expressed in OA and it may promote the production of mature miR-203 to increase apoptosis of chondrocytes induced by LPS.
Other information
Title:

Circular RNA Circ_0038467 promotes the maturation of miRNA-203 to increase lipopolysaccharide-induced apoptosis of chondrocytes.

Journal: Open Med (Wars)
Published: 2023/6/12
PubMed ID: 37305524