circRNA basic information
circBase ID: -
Name: hsa_circ_FAT1
Synonym: circFAT1
Host Gene: hsa-miR-375
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC7A11
Associated microRNA: hsa-miR-375
Biological function: The underexpression of circFAT1 with siRNA plasmids significantly suppressed the proliferation, invasion and clone formation of MM cell line
Molecular mechanism: circFAT1/hsa-miR-375/SLC7A11 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

circFAT1 promotes the proliferation, invasion and clone formation of malignant melanoma cells by improving the expression level of SLC7A11 via sponging miR-375.
Other information
Title:

CircFAT1 promotes the proliferation and invasion of malignant melanoma through miR375-SLC7A11 signal axis.

Journal: Anticancer Agents Med Chem
Published: 2023/6/12
PubMed ID: 37303180