circRNA basic information
circBase ID: -
Name: hsa_circ_FOXK2
Synonym: circFOXK2
Host Gene: hsa-miR-149-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: NSCLC (H661, SPC-A1, H460, A549), normal human lung epithelial (BEAS-2B)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: IL-6
Associated microRNA: hsa-miR-149-3p
Biological function: circFOXK2 stimulated NSCLC cell proliferation, migration and invasion in vitro
Molecular mechanism: circFOXK2/hsa-miR-149-3p/IL-6 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Overall, this research verified that circFOXK2 enhances the tumorigenesis of NSCLC through the miR-149-3p/IL-6 axis.
Other information
Title:

The Circular RNA circFOXK2 Enhances the Tumorigenesis of Non-Small Cell Lung Cancer Through the miR-149-3p/IL-6 Axis.

Journal: Biochem Genet
Published: 2023/5/31
PubMed ID: 37256441