circRNA basic information
circBase ID: -
Name: hsa_circ_ANXA7
Synonym: Circ-ANXA7
Host Gene: hsa-miR-545-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCND1
Associated microRNA: hsa-miR-545-3p
Biological function: Circ-ANXA7 combined with miR-545-3p, which targeted CCND1 to expedite A549/DDP cell proliferation, migration, invasion, DDP resistance, but inhibited cell apoptosis.
Molecular mechanism: circ-ANXA7/hsa-miR-545-3p/CCND1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ-ANXA7 enhances DDP resistance in NSCLC via absorbing miR-545-3p to target CCND1 and might be a latent therapeutic target for NSCLC.
Other information
Title:

Circular RNA-AnnexinA7 accelerates cisplatin resistance in non-small cell lung cancer via modulating microRNA-545-3p to mediate Cyclin D1.

Journal: Acta Biochim Pol
Published: 2023/5/23
PubMed ID: 37220402