circRNA basic information
circBase ID: -
Name: hsa_circ_RASA2
Synonym: circRASA2
Host Gene: hsa-miR-543
 
 
 
Disease basic information
DO ID:
 824
DO name: periodontitis
Disease details: periodontitis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TRAF6
Associated microRNA: hsa-miR-543
Biological function: knockdown of circRASA2 promoted proliferation, migration and osteogenic differentiation ability of PDLCs under LPS treatment
Molecular mechanism: circRASA2/hsa-miR-543/TRAF6 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

circRASA2 accelerated the pathological process of periodontitis in vitro through miR-543/TRAF6 axis, and might improve periodontitis by targeting down the expression of circRASA2.
Other information
Title:

[Effect of circRASA2 targeting miR-543/TRAF6 axis on LPS-induced periodontal ligament cell proliferation and osteogenic differentiation].

Journal: Shanghai Kou Qiang Yi Xue
Published: 2023/5/8
PubMed ID: 37153995