circRNA basic information
circBase ID: hsa_circ_0104345
Name: hsa_circ_IQCH
Synonym: circ_0104345
Host Gene: hsa-miR-876-3p
 
 
 
Disease basic information
DO ID:
1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human mammary epithelial cell line (MCF-10A), BC cell lines (MCF-7, SKBR3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZBTB20
Associated microRNA: hsa-miR-876-3p
Biological function: Circ_0104345 knockdown inhibited cell proliferation, migration, invasion, and enhanced cell apoptosis
Molecular mechanism: circ_0104345/hsa-miR-876-3p/ZBTB20 axis, miRNA sponge
Survival: -
Supported No.:
2
Description:

In this study, we demonstrated, for the first time, the crucial regulation of the new circ_0104345/miR-876-3p/ZBTB20 axis in the biological phenotypes of BC cells.

Other information
Title:

A Novel circ_0104345/miR-876-3p/ZBTB20 Axis Regulates the Proliferation, Migration, Invasion, and Apoptosis of Breast Cancer Cells.

Journal: Biochem Genet
Published: 2023/5/6
PubMed ID: 37148331