circRNA basic information
circBase ID: hsa_circ_0001727
Name: hsa_circ_ZKSCAN1
Synonym: circ-ZKSCAN1
Host Gene: hsa-miR-185-5p
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: LUAD cell lines (A549, PC-9), HBE1 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TAGLN2
Associated microRNA: hsa-miR-185-5p
Biological function: circ-ZKSCAN1 knockdown weakened DDP resistance and suppressed cell viability, migration, invasion, and glycolysis in LUAD
Molecular mechanism: Circ-ZKSCAN1/hsa-miR-185-5p/TAGLN2 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ-ZKSCAN1 promoted LUAD tumorigenesis and DDP resistance by regulating miR-185-5p/TAGLN2 axis.
Other information
Title:

CircRNA ZKSCAN1 promotes lung adenocarcinoma progression by miR-185-5p/TAGLN2 axis.

Journal: Thorac Cancer
Published: 2023/4/28
PubMed ID: 37105934