circRNA basic information
circBase ID: -
Name: hsa_circ_Smox
Synonym: circSmox
Host Gene: hsa-miR-340-5p
 
 
 
Disease basic information
DO ID:
 319
DO name: spinal cord disease
Disease details: spinal cord injury
Species: human
Species details: human
Sample type: cell line
Sample type details: Undifferentiated PC12 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Smurf1
Associated microRNA: hsa-miR-340-5p
Biological function: circSmox silencing alleviated LPS-induced apoptosis and inflammation in PC12 cells in vitro
Molecular mechanism: circSmox/hsa-miR-340-5p/Smurf1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircSmox enhances LPS-induced apoptosis and inflammation via miR-340-5p/Smurf1 axis, providing an exciting view of the potential involvement of circSmox in SCI pathogenesis.
Other information
Title:

CircSmox knockdown alleviates PC12 cell apoptosis and inflammation in spinal cord injury by miR-340-5p/Smurf1 axis.

Journal: Immun Inflamm Dis
Published: 2023/4/27
PubMed ID: 37102659