circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_17725
Host Gene: -
 
 
 
Disease basic information
DO ID:
 848
DO name: arthritis
Disease details: arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: FAM46C
Associated microRNA: -
Biological function: circRNA_17725 could inhibit the proliferation but enhance the apoptosis of macrophages
Molecular mechanism: circRNA_17725/hsa-miR-4668-5p/FAM46C axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

This study has suggested that circRNA_17725 regulated macrophage proliferation, apoptosis, inflammation, and polarization by sponging miR-4668-5p and upregulating FAM46C in RA.
Other information
Title:

circRNA_17725 Promotes Macrophage Polarization towards M2 by Targeting FAM46C to Alleviate Arthritis.

Journal: Mediators Inflamm
Published: 2023/4/11
PubMed ID: 37035757