circRNA basic information
circBase ID: hsa_circ_0003028
Name: hsa_circ_FUT8
Synonym: circ_0003028
Host Gene: hsa-miR-1305, hsa-miR-1322
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A549, HCC827 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC5A1
Associated microRNA: hsa-miR-1305, hsa-miR-1322
Biological function: overexpression of circ_0003028 could increase the proliferation and glycolytic capacity and restrain the apoptosis of NSCLC cells, and circ_0003028 silencing played the opposite role to circ_0003028 overexpression
Molecular mechanism: circ_0003028/hsa-miR-1305, hsa-miR-1322/SLC5A1 axis, miRNA sponge
Survival: poor
Supported No.:
 3
Description:

Circ_0003028 could accelerate the malignant behaviors and glycolytic capacity of NSCLC cells via a mechanism that may be related to miR-1305 or the miR-1322/SLC5A1 axis.
Other information
Title:

Circ_0003028 enhances the proliferation and glycolytic capacity and suppresses apoptosis in non-small cell lung cancer cells via the miR-1305/miR-1322-SLC5A1 axis.

Journal: Ann Transl Med
Published: 2023/4/4
PubMed ID: 37007569