circRNA basic information
circBase ID: hsa_circ_0044073
Name: hsa_circ_GRN
Synonym: circ_0044073
Host Gene: hsa-miR-377-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human vascular smooth muscle cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AURKA
Associated microRNA: hsa-miR-377-3p
Biological function: Either circ_0044073 knockdown or miR-377-3p overexpression could impair Ox-LDL-induced human VSMC proliferation, migration, invasion, and inflammation
Molecular mechanism: circ_0044073/hsa-miR-377-3p/AURKA axis, miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0044073 promoted AS progression by elevating AURKA expression by functioning as a miR-377-3p sponge.
Other information
Title:

Ox-LDL-Induced Vascular Smooth Muscle Cell Dysfunction Partly Depends on the Circ_0044073/miR-377-3p/AURKA Axis in Atherosclerosis.

Journal: Int Heart J
Published: 2023/4/3
PubMed ID: 37005319