circRNA basic information
circBase ID: hsa_circ_0005100
Name: hsa_circ_FMN2
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human CRC cells (HCT116, KM12), normal colonic epithelial cells (NCM460)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MSI1
Associated microRNA: hsa-miR-338-3p
Biological function: Overexpressed exosomal circ_FMN2 could promote CRC cell proliferation, metastasis, and suppress apoptosis
Molecular mechanism: Circ_FMN2/hsa-miR-338-3p/MSI1 axis, miRNA sponge
Survival: -
Supported No.:
 4
Description:

Exosomal circ_FMN2 accelerated CRC progression through miR-338-3p/MSI1 axis, revealing that exosomal circ_FMN2 might be a target for CRC treatment.
Other information
Title:

Exosomal Circ_FMN2 Derived from the Serum of Colorectal Cancer Patients Promotes Cancer Progression by miR-338-3p/MSI1 Axis.

Journal: Appl Biochem Biotechnol
Published: 2023/3/31
PubMed ID: 36995659