circRNA basic information
circBase ID: -
Name: hsa_circ_circCDKN2B-AS
Synonym: circCDKN2B-AS_006
Host Gene: hsa-miR-1258
 
 
 
Disease basic information
DO ID:
 7148
DO name: rheumatoid arthritis
Disease details: rheumatoid arthritis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RASFs, NSFs, MH7A
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: RUNX1
Associated microRNA: hsa-miR-1258
Biological function: CircCDKN2B-AS_006 was upregulated in synovium samples from patients with RA and promoted the tumor-like proliferation, migration, and invasion of RASFs
Molecular mechanism: CircCDKN2B-AS_006/hsa-miR-1258/RUNX1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

CircCDKN2B-AS_006 promoted the proliferation, migration, and invasion of RASFs by modulating the miR-1258/RUNX1 axis.
Other information
Title:

Circular RNA CircCDKN2B-AS_006 Promotes the Tumor-like Growth and Metastasis of Rheumatoid Arthritis Synovial Fibroblasts by Targeting the miR-1258/RUNX1 Axis.

Journal: Int J Mol Sci
Published: 2023/3/30
PubMed ID: 36982956