circRNA basic information
circBase ID: hsa_circ_0008450
Name: hsa_circ_CMTM3
Synonym: circ_0008450
Host Gene: hsa-miR-1224-5p
 
 
 
Disease basic information
DO ID:
 10881
DO name: hand, foot and mouth disease
Disease details: keloid-derived fibroblast
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGFBP5
Associated microRNA: hsa-miR-1224-5p
Biological function: Circ_0008450 silencing inhibited KD-derived fibroblast proliferation, cell cycle, and motility and promoted apoptosis.
Molecular mechanism: circ_0008450/hsa-miR-1224-5p/IGFBP5 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Circ_0008450 promoted KD-derived fibroblast proliferation, migration, and invasion and repressed apoptosis via sponging miR-1224-5p and elevating IGFBP5.
Other information
Title:

Circ_0008450 regulates keloid-derived fibroblast proliferation, migration, invasion and apoptosis with increased IGFBP5 through sponging miR-1224-5p.

Journal: Burns
Published: 2023/3/15
PubMed ID: 36918335