circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_0046366
Host Gene: hsa-miR-34a
 
 
 
Disease basic information
DO ID:
 9452
DO name: fatty liver disease
Disease details: hepatocellular steatosis
Species: human
Species details: human
Sample type: cell line
Sample type details: HepG2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PPARalpha
Associated microRNA: hsa-miR-34a
Biological function: -
Molecular mechanism: normalization of PPAR signaling
Survival: -
Supported No.:
 1
Description:

Dysregulation of circRNA_0046366/miR-34a/PPARalpha signaling may be a novel epigenetic mechanism underlying hepatocellular steatosis. circRNA_0046366 serves as a potential target for the treatment of hepatic steatosis.
Other information
Title:

circRNA_0046366 inhibits hepatocellular steatosis by normalization of PPAR signaling.

Journal: World J Gastroenterol
Published: 2018/2/3
PubMed ID: 29391755