circRNA basic information
circBase ID: -
Name: hsa_circ_CAMSAP1
Synonym: circCAMSAP1
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: EC cell lines (HEC-1A, HEC-1B, KLE), endome-trial endothelial cells (hEEC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAPK1
Associated microRNA: hsa-miR-370-3p
Biological function: Functional test results clarified transfection of si-circCAMSAP1 or miR-370-3p-mimic refrained cancer cell proliferation, migration and invasion, but motivated cancer cell apoptosis
Molecular mechanism: circCAMSAP1/hsa-miR-370-3p/MAPK1 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

All in all, the results of this study convey silencing circCAMSAP1 refrains the malignant behavior of EC by controlling miR-370-3p /MAPK1 axis.
Other information
Title:

Silencing circCAMSAP1 suppresses malignant behavior of endometrial cancer by targeting microRNA-370-3p/MAPK1.

Journal: Acta Biochim Pol
Published: 2023/3/2
PubMed ID: 36857620