circRNA basic information
circBase ID: -
Name: hsa_circ_NT5C2
Synonym: -
Host Gene: hsa-miR-448
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-448
Biological function: promoted proliferation and invasion while inhibits apoptosis
Molecular mechanism: sponged hsa-miR-448
Survival: -
Supported No.:
 2
Description:

our study investigates the circRNAs expression profiles and determines the function of circ-NT5C2 in osteosarcoma tumorigenesis, which might serve as a novel therapeutic target of osteosarcoma patients.
Other information
Title:

Circular RNA circ-NT5C2 acts as an oncogene in osteosarcoma proliferation and metastasis through targeting miR-448.

Journal: Oncotarget
Published: 2018/2/1
PubMed ID: 29383123