circRNA basic information
circBase ID: -
Name: hsa_circ_HSPG2
Synonym: circHSPG2
Host Gene: hsa-miR-1184
 
 
 
Disease basic information
DO ID:
9408
DO name: acute myocardial infarction
Disease details: acute myocardial Infarction
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human AC16 cardiomyocytes
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAP3K2
Associated microRNA: hsa-miR-1184
Biological function: CircHSPG2 knockdown alleviated hypoxia-induced AC16 cell injury
Molecular mechanism: circHSPG2/hsa-miR-1184/MAP3K2 axis, miRNA sponge
Survival: -
Supported No.:
1
Description:

CircHSPG2 knockdown protected AC16 cells from hypoxia-induced injury by regulating the miR-1184/MAP3K2 cascade.

Other information
Title:

CircHSPG2 knockdown attenuates hypoxia-induced apoptosis, inflammation, and oxidative stress in human AC16 cardiomyocytes by regulating the miR-1184/MAP3K2 axis.

Journal: Cell Stress Chaperones
Published: 2023/2/23
PubMed ID: 36810972