circRNA basic information
circBase ID: -
Name: hsa_circ_PPFIA1
Synonym: circPPFIA1
Host Gene: hsa-miR-1299
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: EC109 , KYSE150 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TXNRD1
Associated microRNA: hsa-miR-1299
Biological function: Radiosensitivity was enhanced in ESCC cells after downregulation of circPPFIA1
Molecular mechanism: circPPFIA1/hsa-miR-1299/TXNRD1 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

All experimental data showed that knockdown of circPPFIA1 contributed to radiosensitivity in ESCC by inducing miR-1299-related downregulation of TXNRD1.
Other information
Title:

Downregulation of circPPFIA1 elevates radiosensitivity via miR-1299-mediated TXNRD1 inhibition in esophageal squamous cell carcinoma.

Journal: Clin Exp Pharmacol Physiol
Published: 2023/2/18
PubMed ID: 36797846