In conclusion, propofol restrained NSCLC growth by downregulating circ_0000735, which functioned as a miR-153-3p sponge and regulated ITGB1 expression via adsorbing miR-153-3p. This study provides evidence to support that propofol curbs NSCLC progression by regulating circRNA expression.
Propofol-mediated circ_0000735 downregulation restrains tumor growth by decreasing integrin-beta1 expression in non-small cell lung cancer.