circRNA basic information
circBase ID: -
Name: hsa_circ_BNC2
Synonym: circBNC2
Host Gene: hsa-miR-223-3p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-223-3p
Biological function: In-vitro complement experiments showed that overexpression of circBNC2 significantly decreased the malignant behavior of EOC
Molecular mechanism: circBNC2/hsa-miR-223-3p/BNC2 axis, miRNA sponge
Survival: -
Supported No.:
 2
Description:

Overexpression of circBNC2 decreased proliferation, migration, and invasion of EOC cells by regulating the miR-223-3p/ LARP4 axis, suggesting that circBNC2/miR-223-3p/ LARP4 axis may be a potential regulatory mechanism for the treatment of EOC.
Other information
Title:

CircBNC2 affects epithelial ovarian cancer progression through the miR-223-3p/ LARP4 axis.

Journal: Anticancer Drugs
Published: 2023/2/3
PubMed ID: 36730544