circRNA basic information
circBase ID: -
Name: hsa_circ_PWWP2A
Synonym: circPWWP2A
Host Gene: hsa-miR-223-3p
 
 
 
Disease basic information
DO ID:
 850
DO name: lung disease
Disease details: lung inflammation and fibrosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NLRP3
Associated microRNA: hsa-miR-223-3p
Biological function: -
Molecular mechanism: circPWWP2A/hsa-miR-223-3p/NLRP3 axis, miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our study found that circPWWP2A could adsorb miR-223_3p to regulate NLRP3 after silica stimulation in pulmonary fibrosis.
Other information
Title:

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles alleviated silica induced lung inflammation and fibrosis in mice via circPWWP2A/miR-223-3p/NLRP3 axis.

Journal: Ecotoxicol Environ Saf
Published: 2023/1/17
PubMed ID: 36646008