circRNA basic information
circBase ID: -
Name: rno_circ_Fhit
Synonym: circFhit
Host Gene: -
 
 
 
Disease basic information
DO ID:
 936
DO name: brain disease
Disease details: neuropathic pain
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HNRNPK, CDK9, RNF40
Associated microRNA: -
Biological function: -
Molecular mechanism: circFhit/HNRNPK complex
Survival: -
Supported No.:
 1
Description:

In summary, we revealed that the exon-intron circFhit contributes to GABAergic neuron-mediated NK1R+ neuronal hyperexcitation and neuropathic pain via regulating Fhit in cis.
Other information
Title:

CircFhit Modulates GABAergic Synaptic Transmission via Regulating the Parental Gene Fhit Expression in the Spinal Dorsal Horn in a Rat Model of Neuropathic Pain.

Journal: Neurosci Bull
Published: 2023/1/14
PubMed ID: 36637791